{"id":951,"date":"2023-12-07T08:49:37","date_gmt":"2023-12-07T00:49:37","guid":{"rendered":"http:\/\/www.chinrilymedica.cn\/?p=951"},"modified":"2023-12-07T11:05:59","modified_gmt":"2023-12-07T03:05:59","slug":"%e5%9f%ba%e4%ba%8e%e5%86%88%e7%94%b0%e9%85%b8%e4%b8%ad%e5%bf%83%e7%89%87%e6%ae%b5%ef%bc%88c19-c27%ef%bc%89%e8%ae%be%e8%ae%a1%e6%96%b0pp2a%e6%b4%bb%e5%8c%96%e7%9a%84%e8%8d%af%e7%89%a9%ef%bc%8c%e4%b8%ba","status":"publish","type":"post","link":"http:\/\/www.chinrilymedica.cn\/?p=951","title":{"rendered":"\u57fa\u4e8e\u5188\u7530\u9178\u4e2d\u5fc3\u7247\u6bb5\uff08C19-C27\uff09\u8bbe\u8ba1\u65b0pp2a\u6d3b\u5316\u7684\u836f\u7269\uff0c\u4e3aAD\u65b0\u836f\u5f00\u53d1\u5f00\u8f9f\u65b0\u9014\u5f84"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-801\" src=\"http:\/\/www.chinrilymedica.cn\/wp-content\/uploads\/2022\/09\/PDF.jpg\" alt=\"\" width=\"25\" height=\"25\" \/><a href=\"http:\/\/www.chinrilymedica.cn\/wp-content\/uploads\/2023\/12\/C-glycosides-analogues-of-the-okadaic-acid-central-fragment-exert-1.pdf\">C-glycosides analogues of the okadaic acid central fragment exert<\/a><\/p>\n<p>\u86cb\u767d\u78f7\u9178\u91762A \u6d3b\u6027\u7684\u4efb\u4f55\u7f3a\u9677\u90fd\u662f\u5bfc\u81f4\u4e25\u91cd\u75c5\u7406\u7684\u539f\u56e0\u3002\u4f8b\u5982\uff0c\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u4e3b\u8981\u7ec4\u7ec7\u75c5\u7406\u5b66\u7279\u5f81\u4e4b\u4e00\u662f\u795e\u7ecf\u539f\u7ea4\u7ef4\u7f20\u7ed3\uff0c\u5b83\u4eec\u4e3b\u8981\u7531\u8fc7\u5ea6\u78f7\u9178\u5316\u7684tau\u86cb\u767d\u7ec4\u6210\u3002\u8fd9\u79cdtau\u78f7\u9178\u5316\u7684\u53d8\u5316\u4e0ePP2A\u6d3b\u6027\u6291\u5236\u53caAD\u60a3\u8005\u76f8\u5173\u3002<\/p>\n<p><span class=\"fontstyle0\">\u8fd9\u662fRaquel L. Arribas\u7b49\u897f\u73ed\u7259\u7814\u7a76\u8005\u4eca\u5e74\uff082023\u5e74\uff09\u521a\u53d1\u8868\u7684\u7814\u7a76\u6210\u679c\u3002<\/span><\/p>\n<p>PP2A\u6291\u5236\u5242\u5188\u7530\u9178(OA)\u7684\u4e2d\u5fc3\u7247\u6bb5C19-C27\uff0c\u8fd9\u4e2a\u4e2d\u5fc3\u90e8\u5206\u4e0d\u53d1\u6325\u6291\u5236\u4f5c\u7528\uff0c\u4f46\u80fd\u4e0ePP2A\u6291\u5236\u5242\u7ade\u4e89\uff0c\u4ece\u800c\u6062\u590d\u78f7\u9178\u9176\u6d3b\u6027\u3002\u8bc1\u660e\u4e86\u8fd9\u4e2a\u5047\u8bbe\u5316\u5408\u7269\u5728\u4e0ePP2A\u635f\u4f24\u76f8\u5173\u7684\u795e\u7ecf\u53d8\u6027\u6a21\u578b\u4e2d\u663e\u793a\u51fa\u826f\u597d\u7684\u795e\u7ecf\u4fdd\u62a4\u4f5c\u7528\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-957\" src=\"http:\/\/www.chinrilymedica.cn\/wp-content\/uploads\/2023\/12\/\u65e0\u6807\u9898.png\" alt=\"\" width=\"536\" height=\"331\" \/><\/p>\n<p>\u5176\u4e2d\u5316\u5408\u7269ITH12711\u901a\u8fc7\u78f7\u9178\u5316\u80bd\u5e95\u7269\u548cwestern-blot\u5206\u6790\u6d4b\u5b9a\uff0c\u80fd\u591f\u589e\u52a0PP2A\u7684\u50ac\u5316\u6d3b\u6027\uff1b\u901a\u8fc7PAMPA\u6d4b\u91cf\u8bc1\u660e\u5177\u6709\u826f\u597d\u7684\u8111\u7a7f\u900f\u6027\uff1b\u80fd\u591f\u589e\u5f3a\u56e0lps\u8bf1\u5bfc\u7684\u8bb0\u5fc6\u635f\u4f24\u5c0f\u9f20\u5728\u7269\u4f53\u8bc6\u522b\u80fd\u529b\u3002<\/p>\n<p>\u8fd9\u9879\u7814\u7a76\u6210\u679c\u53ef\u4ee5\u9a8c\u8bc1\u4e86\u57fa\u4e8eOA\u4e2d\u5fc3\u7247\u6bb5\u8bbe\u8ba1\u65b0\u7684pp2a\u6d3b\u5316\u836f\u7269\u7684\u65b9\u6cd5\uff0c\u4e3a\u5f00\u53d1AD\u65b0\u836f\u5f00\u8f9f\u65b0\u9014\u5f84\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>C-glycosides analogues of the okadaic acid central frag &#8230; <a title=\"\u57fa\u4e8e\u5188\u7530\u9178\u4e2d\u5fc3\u7247\u6bb5\uff08C19-C27\uff09\u8bbe\u8ba1\u65b0pp2a\u6d3b\u5316\u7684\u836f\u7269\uff0c\u4e3aAD\u65b0\u836f\u5f00\u53d1\u5f00\u8f9f\u65b0\u9014\u5f84\" class=\"read-more\" href=\"http:\/\/www.chinrilymedica.cn\/?p=951\" aria-label=\"\u7ee7\u7eed\u9605\u8bfb\u57fa\u4e8e\u5188\u7530\u9178\u4e2d\u5fc3\u7247\u6bb5\uff08C19-C27\uff09\u8bbe\u8ba1\u65b0pp2a\u6d3b\u5316\u7684\u836f\u7269\uff0c\u4e3aAD\u65b0\u836f\u5f00\u53d1\u5f00\u8f9f\u65b0\u9014\u5f84\">\u9605\u8bfb\u66f4\u591a<\/a><\/p>\n","protected":false},"author":2,"featured_media":494,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"yes","footnotes":""},"categories":[11],"tags":[],"class_list":["post-951","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-study"],"_links":{"self":[{"href":"http:\/\/www.chinrilymedica.cn\/index.php?rest_route=\/wp\/v2\/posts\/951","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.chinrilymedica.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.chinrilymedica.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.chinrilymedica.cn\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www.chinrilymedica.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=951"}],"version-history":[{"count":5,"href":"http:\/\/www.chinrilymedica.cn\/index.php?rest_route=\/wp\/v2\/posts\/951\/revisions"}],"predecessor-version":[{"id":958,"href":"http:\/\/www.chinrilymedica.cn\/index.php?rest_route=\/wp\/v2\/posts\/951\/revisions\/958"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.chinrilymedica.cn\/index.php?rest_route=\/wp\/v2\/media\/494"}],"wp:attachment":[{"href":"http:\/\/www.chinrilymedica.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=951"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.chinrilymedica.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=951"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.chinrilymedica.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=951"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}